Kristie A Blum Selected Research

milatuzumab

6/2015	The combination of milatuzumab, a humanized anti-CD74 antibody, and veltuzumab, a humanized anti-CD20 antibody, demonstrates activity in patients with relapsed and refractory B-cell non-Hodgkin lymphoma.
12/2011	FTY720 increases CD74 expression and sensitizes mantle cell lymphoma cells to milatuzumab-mediated cell death.
4/2011	Combination anti-CD74 (milatuzumab) and anti-CD20 (rituximab) monoclonal antibody therapy has in vitro and in vivo activity in mantle cell lymphoma.

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Kristie A Blum Research Topics

Disease

25	Neoplasms (Cancer) 01/2022 - 11/2002
21	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 10/2022 - 01/2007
20	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 11/2021 - 01/2009
17	Non-Hodgkin Lymphoma (Lymphosarcoma) 10/2022 - 11/2004
15	Lymphoma (Lymphomas) 07/2022 - 08/2003
14	Hodgkin Disease (Hodgkin's Disease) 12/2021 - 07/2007
10	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 06/2020 - 10/2008
10	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 01/2019 - 08/2003
6	Neutropenia 06/2020 - 07/2010
5	Disease Progression 03/2016 - 03/2010
5	Leukemia 11/2015 - 12/2006
3	Diarrhea 10/2019 - 03/2014
3	B-Cell Lymphoma (Lymphoma, B Cell) 12/2017 - 08/2003
3	Exanthema (Rash) 11/2016 - 11/2002
3	Tumor Lysis Syndrome 03/2013 - 03/2009
2	Fatigue 06/2020 - 11/2015
2	Hemorrhage 09/2017 - 08/2015
2	Febrile Neutropenia 01/2017 - 07/2010
2	Thrombocytopenia (Thrombopenia) 01/2017 - 07/2010
2	Lymphadenopathy 03/2013 - 12/2009
2	Cytokine Release Syndrome 12/2009 - 03/2009
1	Hypersensitivity (Allergy) 01/2022
1	Breast Neoplasms (Breast Cancer) 01/2022
1	Renal Cell Carcinoma (Grawitz Tumor) 01/2022
1	Headache (Headaches) 01/2022
1	Hypertension (High Blood Pressure) 01/2022
1	Melanoma (Melanoma, Malignant) 01/2022
1	Sarcoma (Soft Tissue Sarcoma) 01/2022
1	Vomiting 10/2019
1	Nausea 10/2019
1	Multiple Myeloma 01/2019
1	Hypoalbuminemia 12/2017
1	Atrial Fibrillation 09/2017
1	Hematologic Neoplasms (Hematological Malignancy) 09/2017
1	Stroke (Strokes) 09/2017
1	Tetraploidy 08/2017
1	Thrombosis (Thrombus) 11/2015
1	Prolymphocytic Leukemia 08/2015
1	Infections 08/2015
1	Agammaglobulinemia (Hypogammaglobulinemia) 07/2015

Drug/Important Bio-Agent (IBA)

21	Rituximab (Mabthera)FDA Link 01/2022 - 08/2003
21	ibrutinibIBA 01/2019 - 06/2011
11	Lenalidomide (CC 5013)FDA Link 06/2020 - 10/2008
9	Agammaglobulinaemia Tyrosine KinaseIBA 01/2018 - 06/2011
9	alvocidib (flavopiridol)IBA 04/2015 - 01/2007
7	Bortezomib (Velcade)FDA Link 01/2020 - 07/2007
6	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2019 - 02/2013
5	Prednisone (Sone)FDA LinkGeneric 01/2019 - 06/2015
5	Vincristine (Oncovin)FDA LinkGeneric 01/2019 - 06/2015
5	Cyclin-Dependent Kinases (cdk Proteins)IBA 01/2014 - 01/2007
4	Bendamustine Hydrochloride FDA Link 01/2020 - 01/2015
4	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2019 - 11/2016
3	Monoclonal AntibodiesIBA 01/2022 - 08/2003
3	Etoposide (VP 16)FDA LinkGeneric 01/2019 - 06/2015
3	Alkylating AgentsIBA 01/2017 - 03/2014
3	idelalisibIBA 01/2017 - 03/2014
3	Dacarbazine (DIC)FDA LinkGeneric 06/2015 - 03/2010
3	milatuzumabIBA 06/2015 - 04/2011
3	AntibodiesIBA 06/2015 - 08/2003
2	Gemcitabine FDA Link 01/2020 - 11/2002
2	ofatumumab FDA Link 10/2019 - 08/2015
2	Pharmaceutical PreparationsIBA 01/2019 - 12/2011
2	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 09/2017 - 11/2015
2	Proteins (Proteins, Gene)FDA Link 12/2016 - 01/2010
2	Bleomycin (Blenoxane)FDA LinkGeneric 06/2015 - 02/2013
2	Vinblastine (Vinblastine Sulfate)FDA Link 06/2015 - 02/2013
2	Transaminases (Aminotransferases)IBA 03/2014 - 11/2011
2	GlucuronidesIBA 03/2013 - 03/2009
1	mRNA VaccinesIBA 10/2022
1	apolizumabIBA 01/2022
1	NVP-BKM120IBA 01/2022
1	AntigensIBA 01/2022
1	HLA-DR Antigens (HLA-DR)IBA 01/2022
1	Immunoglobulin G (IgG)IBA 01/2022
1	B 31IBA 10/2019
1	CreatinineIBA 01/2019
1	palbociclibIBA 01/2019
1	ImidesIBA 01/2019
1	MLN 8237IBA 01/2017
1	PanobinostatIBA 01/2017
1	Biological ProductsIBA 12/2016
1	Adenosine Monophosphate (AMP)IBA 11/2016
1	fostamatinibIBA 02/2016
1	Syk KinaseIBA 02/2016
1	Heparin (Liquaemin)FDA LinkGeneric 11/2015
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 07/2015
1	Type C PhospholipasesIBA 07/2015
1	Mechlorethamine (Nitrogen Mustard)FDA Link 06/2015
1	veltuzumabIBA 06/2015

Therapy/Procedure

32	Therapeutics 07/2022 - 08/2003
8	Drug Therapy (Chemotherapy) 12/2021 - 08/2003
8	Stem Cell Transplantation 01/2020 - 11/2004
4	Radiotherapy 12/2021 - 02/2013
3	Combination Drug Therapy (Combination Chemotherapy) 06/2015 - 08/2003
2	Renal Dialysis (Hemodialysis) 01/2014 - 12/2009
2	Hematopoietic Stem Cell Transplantation 10/2008 - 04/2008
1	Immunotherapy 01/2019
1	Autologous Transplantation 09/2018
1	Induction Chemotherapy 03/2017
1	Drug Tapering 11/2016